Thursday, September 29, 2016

Boots Gripe Mixture 1 Month Plus





1. Name Of The Medicinal Product



Children's Gripe Mixture or Gripe Mixture or Infant Sugar Free Gripe Mixture or Children's 1 Month Plus Gripe Mixture or Boots Gripe Mixture 1 Month Plus


2. Qualitative And Quantitative Composition








Active ingredient




% Quantity




Sodium Bicarbonate EP




1.0w/v



3. Pharmaceutical Form



Liquid



4. Clinical Particulars



4.1 Therapeutic Indications



For the relief of wind and griping pains.



4.2 Posology And Method Of Administration



Babies up to 1 month: Not Recommended.



Infants 1 - 6 months: 5ml. Infants 6 months - 1 Year: 10ml.



The above doses may be repeated before or after each feed up to six times in 24 hours if needed.



Not recommended for children over 1 year.



For oral administration.



4.3 Contraindications



Hypersensitivity to any of the ingredients.



Babies under one month of age or over one year of age.



4.4 Special Warnings And Precautions For Use



Keep all medicines out of the reach of children.



Not to be given to babies under one month of age or over 1 year.



4.5 Interaction With Other Medicinal Products And Other Forms Of Interaction



There are no clinically significant interactions.



4.6 Pregnancy And Lactation



The safety of this medicine during pregnancy and lactation has not been established but is not considered to constitute a hazard during these periods.



4.7 Effects On Ability To Drive And Use Machines



No adverse effects known



4.8 Undesirable Effects



Rarely hypersensitivity reactions



4.9 Overdose



Overdosage with this medicine may give rise to the symptoms of hypernatraemia, which may include drowsiness and irritability, pyrexia, tachypnoea and hyperpnoea. In more severe instances of acute sodium overload signs of dehydration and convulsions may occur.



Treatment of hypernatraemia includes repair of any dehydration present and the gradual reduction of plasma sodium. The alkalosis, if present, will respond usually to the treatment of Hypernatraemia. At all times, intensive monitoring of electrolytes and patient's circulation and central nervous system is essential.



5. Pharmacological Properties



5.1 Pharmacodynamic Properties



Sodium Bicarbonate has antacid properties.



5.2 Pharmacokinetic Properties



None stated.



5.3 Preclinical Safety Data



Not applicable.



6. Pharmaceutical Particulars



6.1 List Of Excipients



Lycasin 80/55 Roquette



Glycerol



Sodium citrate



Domiphen bromide



Apple flavour 5112O1E



Purified water



Carbon dioxide



6.2 Incompatibilities



None stated



6.3 Shelf Life



24 months unopened



12 weeks after opening



6.4 Special Precautions For Storage



Do not store above 25°C.



6.5 Nature And Contents Of Container



A clear polythene terephthalate bottle with a polypropylene child resistant closure fitted with an expanded polyethylene liner.



Pack size: 100ml, 150ml, 200ml



6.6 Special Precautions For Disposal And Other Handling



None



7. Marketing Authorisation Holder



The Boots Company Plc



1 Thane Road West



Nottingham NG2 3AA



8. Marketing Authorisation Number(S)



PL 00014/5236



9. Date Of First Authorisation/Renewal Of The Authorisation



Date of First Authorisation: 24 October 1990



Date of Last Renewal: 20 February 1996



10. Date Of Revision Of The Text



November 2001.




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